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Po (voiced by Jack Black) is now living his dream as The Dragon Warrior, protecting the Valley of Peace alongside his friends and fellow kung fu masters, The Furious Five Tigress, Crane, Mantis, Viper and Monkey. But Poâ??s new life of awesomeness is threatened by the emergence of a formidable villain, who plans to use a secret, unstoppable weapon to conquer China and destroy kung fu. It is up to Po and The Furious Five to journey across China to face this threat and vanquish it. But how can Po stop a weapon that can stop kung fu? He must look to his past and uncover the secrets of his mysterious origins; only then will he be able to unlock the strength he needs to succeed.

Alex, Marty, Gloria and Melman are still trying to get back to the Big Apple and their beloved Central Park zoo, but first they need to find the penguins. When they travel to Monte Carlo, they attract the attention of Animal Control after gate crashing a party and are joined by the penguins, King Julian and Co., and the monkeys. How do a lion, zebra, hippo, giraffe, four penguins, two monkeys, three lemurs travel through Europe without attracting attention and get back to New York? They join a traveling circus which they reinvent, Madagascar style.